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The tool is also able to incorporate the effects of “posttranslational” modifications to finished proteins, as well as changes to DNA and RNA known as epigenetic markers.

Mateusz Sikora, the project leader and head of the Dioscuri Centre for Modelling of Posttranslational Modifications, and his team in Krakow and partners at the Max Planck Institute of Biophysics in Frankfurt am Main, Germany, have addressed this challenge by using computers, working together with scientists at Inserm in Paris, Academia Sinica in Tapei and the University of Bremen.

Huang, Y., Xu, L., Sun, Y. & Nabel, G. J. The assembly of Ebola virus nucleocapsid requires virion-associated proteins 35 and 24 and posttranslational modification of nucleoprotein.

Posttranslational detyrosination of the microtubule network influences the mechanical properties of heart cells.

Posttranslational detyrosination of the microtubule network influences the mechanical properties of heart cells.