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These embryonic pluripotent cells within the facial primordium -- the early development form -- may be necessary for forming proper facial structures.

Published online December 13 in Current Biology, the new work reveals how the cells in the primordium use a protein called RhoA to trigger forces that move the group into place in the developing embryo.

For example, if Fog levels were lower than normal, would this unmask the ability of cells in the primordium region to internalize by the mechanism associated with the propagation region?

At around five weeks, a group of cells clump together to form the bipotential primordium.

Bach was able to do this, and what emerged in the current were primordia in music.