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Mekhail notes the discovery is also relevant to premature aging conditions like progeria.

They also plan to model a disease called progeria, in which cells have a genetic mutation that leads to loss of heterochromatin.

At age 3, just hours after the birth of the Kushners’ daughter, Aaron was diagnosed with a rare disease, progeria, in which the body ages rapidly.

Seidman says the team is encouraged by a recent success at using DNA base editing to repair heart cells and other kinds in mice with progeria, a disease that causes children to age rapidly.

Since then, he has also kept up with his research into progeria, his foundation in Italy and his role as a global spokesman for the Progeria Research Foundation.