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Progestin pills have already been available to purchase in the U.K. without prescription since 2021, and the FDA had approved norgestrel, a type of progestin, as a prescription medication in 1973.

These methods prevent pregnancy by releasing estrogen and progestin to stop ovulation and are the most common contraceptives in Europe and North America.

Specifically, the team found that elderly females undergo the same endocrinological changes as a woman in middle age; her estrogens and progestins levels fall, while levels of follicle-stimulating and luteinizing hormones rise.

The progestin-only pill, sometimes called the “mini pill,” contains only progestin.

Opill is part of an older class of contraceptives that contain a single synthetic hormone as opposed to next-generation pills that combine two hormones, estrogen and progestin.