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The researchers now hope to develop an EV-DNA-based prognostic test for metastasis risk, as well as a vaccine-like therapy to enhance tumor EV-DNA signaling and suppress metastasis in patients with early stage cancer.

According to the team, there are predictive, prognostic and diagnostic AI models and solutions that are becoming available for health care practitioners, but how they are used varies widely at different institutions.

"Taken together, expression of mitochondrial BKCa could be used as a prognostic or therapeutic marker in breast cancer patients and presents a potentially new anti-cancer treatment strategy."

These findings point to the potential of developing precise prognostic and therapeutic interventions.

The new guideline extends exercise stress testing recommendations to include children diagnosed with HCM to help determine functional capacity and provide prognostic feedback.