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Tea and chocolate also contain caffeine, which theobromine is related to as part of the purine family of chemicals.

However, with JHU395 treatment, the tumors can still access purine by a recycling or salvage pathway.

“Some people are just genetically able to process those purines in our diet, which is a breakdown product of various foods, better than others,” Bauer said.

The foods most likely to contribute to these inner stalagmites are high in the chemical compound purine, among them venison and foie gras, pheasant and scallops, goose and caviar.

In Xu and co-workers’ synthetic pathway, a UV-induced chemical reduction occurs that leads to the strikingly selective destruction of these unwanted by-products, ultimately producing only the biologically relevant isomers of the purines.