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"I put on weight due to my relationship and things going wrong," she said.

It also means for a lot of overweight people there is a “hormonal deficiency, or at least it doesn’t go up as high”, argues Prof Yeo, which leaves them biologically more hungry and primed to put on weight than someone who is naturally thin.

There is always the risk that someone will put on weight again as stopping treatment means their normal food cravings return.

In the first scientific report of its kind, researchers in Arkansas showed that chickens bred for water conservation continued to put on weight despite heat stress that would normally slow growth.

Despite the high-calorie diet, these animals did not put on weight, showed fewer signs of liver disease and had lower levels of biomarkers that indicate liver damage.