�y��vlog

But long-term use can take a terrible toll on the kidney, causing scarring and other dramatic physical changes that shift the organ's focus from blood filtration to producing renin.

Preliminary data from the Johns Hopkins team point to blood vessel stiffness and renin hormone levels in the blood as potential reasons for the lack of blood pressure variation in mice without the receptor.

The researchers also measured two hormones that are affected by liquorice and that regulate fluid balance: renin and aldosterone.

The disease can be detected by blood tests that measure the levels of aldosterone and renin, an enzyme made in the kidneys that helps control blood pressure, then calculating the ratio between the two.

But in people with primary aldosteronism, aldosterone can be elevated even when renin is low.