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The company Oncolytics Biotech has performed two successful phase 2 trials of a tumor-attacking reovirus, combined with various types of chemotherapy and checkpoint inhibitors, in patients with breast cancer or pancreatic cancer.

Experts at University of Leeds and four other centres now plan to treat more patients with reovirus therapy.

UW-Madison scientists say the virus, dubbed largemouth bass reovirus, is new to science.

Despite the public drubbing, Thompson remains optimistic—not just about reovirus, but also about polio and the many other virus-based immunotherapy treatments being tried in oncology.

Here, we treated patients with a single cycle of intravenous reovirus before planned surgery to resect colorectal cancer metastases in the liver.