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An exceptional response in a patient with metastatic rhabdomyosarcoma was detailed in a publication in Nature Communications in 2020.

The left-hander from Essex was diagnosed with rhabdomyosarcoma - a soft tissue tumour - at the age of one, needing chemotherapy and surgery over 18 months before recovering.

But whole genome sequencing helped doctors identify the type of cancer she has - a rhabdomyosarcoma - a rare cancer that generally affects muscles attached to bones.

The Fairall family drew up a bucket list with Sophie in June, when her "aggressive" cancer - rhabdomyosarcoma - returned and she decided not to have further chemotherapy.

One month later, her mother was diagnosed with a rare cancer called rhabdomyosarcoma that was found in her head and neck.