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Even so, they suggested that their findings “may inform future public health risk-benefit assessments of fluoride.”

“But if you are feeling better, and you know you don’t have a fever, and you’re not using Tylenol or Advil to mask your fever, it’s what I would call a risk-benefit situation.”

Its outsize role in our culture is only one reason it is challenging to fit alcohol into the usual kinds of risk-benefit analyses that apply to so many routine choices.

If some of Russia’s earlier invaders had been “sent home in body bags,” as Veep Biden and others said was necessary at the time, would Putin have later altered his risk-benefit calculus?

The data collected and analyzed in the reviews suggest a risk-benefit ratio that is characterized as unknown, unfavorable, or insufficient on a scientific basis.