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The cousins' first product, a form of santonin used to treat intestinal worms - a common complaint at the time - was an immediate success.

Of this class was Dr Gruff, a man whom I would back against the whole profession for caudle, clyster, castor-oil, or linseed poultice; but who, I rather suspect, never prescribed a dose of chiretta, santonin, or lithia-water in his life.

There were some interesting sensory manifestations, pains in the arms and legs after the injection, but these were removed by santonin or methylene blue.

Treatment.—The most efficient remedy for removing round-worms is Santonin.

For a child of six years the formula would therefore be, 3-1/2 grains of Santonin, mixed with the same quantity of sugar of milk divided into three powders.