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During the latter half of his life Henle’s researches were mainly histological in character, his investigations embracing the minute anatomy of the blood vessels, serous membranes, kidney, eye, nails, central nervous system, &c.

The pericardial milk-spots and thickenings, the tendinous or semi-cartilaginous, indurated patches of serous membranes and of the intima of arteries, are all regarded as manifestations of a chronic inflammation of these tissues.

They have also a ramification of nerves, and the body of the gland has its own system of arterial vessels and absorbents, which are enclosed by a serous membrane.

Certain complications are apt to arise in erysipelas affecting the surface of the body, particularly inflammation of serous membranes, such as the pericardium or pleura.

In order that loss of power from friction may be obviated, the heart is enclosed between two layers of serous membrane, which forms a kind of sac.