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A study at MedUni Vienna's Department of Dermatology was the first to investigate the previously unknown diversity of CAFs in various types of skin cancer -- basal cell carcinoma, squamous cell carcinoma and melanoma -- at molecular and spatial level in single-cell analysis.

Her first cannabis patient was a Jack Russell terrier with a squamous cell carcinoma, a type of skin cancer that causes tumors.

"We called this metric 'untranslated tumor mutation burden' or uTMB and found particularly striking the association between uTMB and lung squamous cell carcinoma as well as head and neck squamous cell carcinoma."

"The squamous epithelia of the esophagus and the columnar epithelia of the stomach meet at the gastroesophageal junction," explains Dr. Naveen Kumar Nirchal, one of the first authors of the study.

"Barrett's esophagus is characterized by the replacement of the resident squamous epithelium of the esophagus by other cell types that are not normally found in this tissue," says the scientist.