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Traces of sterol lipids, which come from cell membranes, have been found in rocks up to 1.6 billion years old.

In the new work, Burke's group worked again with Rienstra's group to find that AmB similarly kills human kidney cells by extracting cholesterol, the most common sterol in people.

But cholesterol, a closely related sterol, performs much the same function in human cells.

Because sterols are found throughout the eukaryotic family tree, they are thought to have been present in the last common ancestor of all modern eukaryotes.

Cholesterol belongs to a family of similar molecules called sterols.