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Previous studies have shown that boosting ketone bodies through diet, exercise and supplementation can be good for brain health and cognition, both in rodents and humans.

A University of California, Riverside, mouse study published in Archives of Toxicology reports that probiotic supplementation can reduce the negative impacts of PBDEs on neurodevelopment, behavior, and metabolism.

However, whether vitamin D supplementation lowers the risk of these diseases and what vitamin D blood levels are needed for better health have been debated for years.

Though some have a genetic basis, at least half are caused by a folate deficiency, and a key 1991 Lancet study showed that 72% of neural tube defects could be prevented with folic acid supplementation.

The authors hope that their manuscript will contribute to the ongoing discourse on vitamin D supplementation guidelines.