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telomere
[ tel-uh-meer, tee-luh‑ ]
noun
- the segment of DNA that occurs at the ends of chromosomes.
telomere
/ ˈɛəˌɪə /
noun
- genetics either of the ends of a chromosome
telomere
/ ĕ′ə-î′,ŧ′ə- /
- Either of the sections of DNA occurring at the extreme ends of each chromosome in a eukaryotic cell. Telomeres consist of highly repetitive sequences of DNA that do not code for proteins, but function as caps to keep chromosomes from fusing together. The length of the telomere influences the stability of genetic information just interior of the telomere, since the nucleotide sequences at the ends of a chromosome are not copied by DNA polymerase. Successive copying can thus shorten telomeres, sometimes to the point that functional genes near the telomeres are lost, and this may play a role in cellular senescence and age-related diseases. In germ cells, stem cells, and some cancer cells, shortened telomeres can be extended by the enzyme telomerase , thus keeping both the telomeres and the genes near them functioning. Most somatic cells do not express telomerase, and the shortening of telomeres during each round of cell division may be part of the natural aging of cells.
telomere
- The long end sequences of a DNA strand occurring at the tip of the chromosomes ; a type of repetitive DNA that usually consists of one hundred to fifteen hundred copies of a single DNA sequence.
Notes
yvlog History and Origins
Origin of telomere1
yvlog History and Origins
Origin of telomere1
Example Sentences
In Mason’s study, telomere changes returned to baseline within days, he said.
Discoveries made during NASA’s study on the Kelly twins found extended time in space also impacts telomeres, the protein structures at the ends of chromosomes that control cellular division.
But telomeres shorten as we age, eventually getting so whittled down that our chromosomes become exposed, and our cells die.
During Mr. Kelly’s year in space, age markers in his DNA known as telomeres grew longer — suggesting, surprisingly, that he had become biologically younger.
The length of telomeres that protect the ends of our chromosomes should be tightly regulated.
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