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Those results, she said, suggest that the gut microbiota in normal-weight children may be more resilient when exposed to xenobiotic substances like BPA.

The findings back earlier studies suggesting that PAHs may disturb the inflammatory response and xenobiotic metabolism in human olfactory mucosa cells, and that ultrafine particles may mediate adverse effects to the brain via the olfactory pathway.

Exposure to emissions from both renewable and fossil diesel significantly altered the expression of genes associated with inflammatory response, xenobiotic metabolism, olfactory signalling and olfactory mucosa integrity.

His team contends that smokers and the many Indians who live with bad air pollution might overexpress a variation of an enzyme, CY1P1A1, that “detoxifies” the lungs and destroys the virus through a previously described phenomenon, “xenobiotic metabolism.”

Symbiotic bacterial metabolites regulate gastrointestinal barrier function via the xenobiotic sensor PXR and Toll-like receptor 4.