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People who use the herbal supplement yohimbe may be getting more, or less, than they bargain for.

Yohimbine, the alkaloid derived from the bark of the African yohimbe tree and the active ingredient in yohimbe supplements, is sold despite little or no evidence for its effectiveness as a weight-loss aid and for treating erectile dysfunction, depression, low libido in women and other ailments.

Those medicinal-mixed drinks were a mixed bag; more on the sweet side — from a bourbon Manhattan done with Yohimbe tincture to give some “stimulant and aphrodisiac” benefits to the aforementioned Viagra-like drink, Chiang Rye, that tasted like liquid dessert.

“I was surprised by the profound lack of science supporting the benefit of ingesting some these ingredients such as carnitine, Yohimbe, and bitter orange,” says Blankson.

The bark from the Yohimbe tree, native to western Africa, can be found in teas, capsules and tablets promoted to treat sexual dysfunction.