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BBC Eye found one pharmaceutical company, Aveo, had been illegally exporting a harmful mix of tapentadol and carisoprodol in countries like Ghana, Nigeria, and Cote D'Ivoire.

The circular from Dr Raghuvanshi, dated to Friday, cited the BBC investigation in his decision to ban all combinations of tapentadol and carisoprodol, which was to be implemented with immediate effect.

Tapentadol is a powerful opioid, and carisoprodol is a muscle relaxant so addictive it is banned in Europe.

Carisoprodol is approved for use in the US, but only for short periods of up to three weeks.

But all contain the same harmful mix of ingredients: tapentadol, a powerful opioid, and carisoprodol, a muscle relaxant so addictive it's banned in Europe.