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They fed pregnant female mice low doses of BPA, BPS, diphenyl sulfone, or a placebo.

As part of its Safe Drinking Water Act review, the EPA also examined levels of dimethoate; 1,3-dinitrobenzene; terbufos and terbufos sulfone in drinking water supplies.

The sulfone drug Dapsone was the drug of choice starting in 1947, but increasing resistance is what prompted the WHO to introduce the current regimen, combining Dapsone with two other drugs.

The annual commemoration was started 60 years ago to raise awareness for a disease that at the time infected almost 10 million people a year, was fast outwitting sulfone drugs, and for which a vaccine seemed impossible because leprosy germs cannot be grown in a test tube.

This 2-substituted 5-nitroimidazole drug is rapidly oxidized in vivo in mice, dogs, and humans to sulfoxide and sulfone metabolites.