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It turns the human brain into a reptilian one and activates the sympathetic nervous system, putting us into fight-or-flight mode — the same one we can get stuck in when we’re chronically lonely.

"Patients with HD have a slightly more active sympathetic nervous system, which is what drives the fight or flight response, and theoretically have more norepinephrine," Schultz explains.

Imai’s team discovered that those neurons send signals to the animal’s fat stores via the sympathetic nervous system, a network of nerves carrying messages from the brain throughout the body.

The resulting activation of the sympathetic nervous system could interfere with sleep, drive inflammation, and disrupt glucose regulation, he adds, all of which have downstream health effects.

In general, faster breathwork practices work by activating the sympathetic nervous system and activating its “fight or flight” mode.