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Higher levels of PFOA, which predicted coronary microvascular disease, were associated with higher levels of amino acids isoleucine and leucine and higher levels of pro-inflammatory cytokines.

Other data from Lamming's lab suggest that overweight and obese Americans may be eating significantly more isoleucine than they need.

Instead, the powdered blend is loaded with leucine, isoleucine, valine, glycine, betaine, taurine and creatine monohydrate.

For example, maple syrup urine disease is caused by a build up of three amino acids: leucine, isoleucine and valine.

In each family, Gleeson's team identified mutations that inactivate the enzyme BCKD-kinase, which normally prevents the body from breaking down branched-chain amino acids called leucine, isoleucine and valine after a meal.